While at college, Sue Perkins was in line to be a teacher, but her flatmate bet her that she could not do a turn at stand-up, and so the course of Sue Perkins's life changed.
Sue Perkins really broke through into the public's awareness when she teamed up with Mel Giedroyc and they became famous as the double-act Mel and Sue.
Initially they appeared on Channel 4's daytime show, Light Lunch, before moving to the evening schedule with Late Lunch.
Additionally Mel and Sue for many years took their act on tour.
In 2002 Sue Perkins appeared on Celebrity Big Brother.
Sue Perkins's recent solo stand-up shows include Spectacle Wearer of the Year and The Disappointing Second Show.
Having appeared previously in the documentary Edwardian Supersize Me, in 2008, Sue Perkins and Giles Coren fronted the BBC Two series The Supersizers Go and The Supersizers Eat.
Also in 2008, Sue Perkins won the BBC series, Maestro.
Sue Perkins studied music to a high level and reached grade 8 on the piano.
She likes football and supports Charlton Athletic.
In 2010, BBC Two commissioned another show with Sue Perkins and Giles Coren, entitled Giles And Sue Live The Good Life, in which they try the self-sufficient lifestyle of Tom and Barbara Good in the BBC sitcom The Good Life.
In 2015, she revealed that she has had a non-cancerous tumour in her pituitary gland for eight years.